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RECRUITING
NCT05274048
Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients
18 Enrollment(s)
3 Study location(s)
INTERVENTIONAL (PHASE1)
Gastric Cancer


Gastrointestinal Cancer


HER2 Gene Mutation
RECRUITING
NCT06467357
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
620 Enrollment(s)
260 Study location(s)
INTERVENTIONAL (PHASE3)
Biliary Tract Cancer
ACTIVE_NOT_RECRUITING
NCT03334617
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
528 Enrollment(s)
45 Study location(s)
INTERVENTIONAL (PHASE2)
Non-Small Cell Lung Cancer
RECRUITING
NCT06533826
TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
357 Enrollment(s)
11 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer


HER2-low Breast Cancer


Metastatic Breast Cancer


HER2-negative Breast Cancer
RECRUITING
NCT06271837
A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors
175 Enrollment(s)
31 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Solid Tumors (Excluding Gastric Cancer and Breast Cancer)
RECRUITING
NCT06750484
Trial of Trastuzumab Deruxtecan in Previously Treated HER2
40 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer Metastatic
ACTIVE_NOT_RECRUITING
NCT03529110
DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]
524 Enrollment(s)
164 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
RECRUITING
NCT07124000
DESTINY-PANTUMOUR04
100 Enrollment(s)
8 Study location(s)
OBSERVATIONAL (None)
Adenocarcinoma (NOS)


Anal Cancer


Bladder Cancer


Cervical Cancer


Endometrial Cancer


Esophageal Cancer


Gall Bladder Cancer


Gastrointestinal Stromal Tumour


Head and Neck Cancer


Liver Cancer


Melanoma


Mouth Cancer


Nasopharangeal Cancer


Neuroendocrine, Gastrointestinal Cancer


Ovarian Cancer


Pancreatic Cancer


Prostate Cancer


Renal Cell Carcinoma


Salivary Gland Cancer


Sarcoma


Small Cell Lung Cancer


Testicular Cancer


Throat Cancer


Thyroid Cancer


Urethral Cancer


Vaginal Cancer


Vulvar Cancer