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RECRUITING
NCT05417594
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
695 Enrollment(s)
32 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Advanced Solid Malignancies
RECRUITING
NCT05408845
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
146 Enrollment(s)
150 Study location(s)
INTERVENTIONAL (PHASE2)
Metastatic Salivary Gland Carcinoma


Recurrent Salivary Gland Carcinoma


Stage III Major Salivary Gland Cancer AJCC v8


Stage IV Major Salivary Gland Cancer AJCC v8


Unresectable Salivary Gland Carcinoma
ACTIVE_NOT_RECRUITING
NCT04493138
Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations
30 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Chronic Myelomonocytic Leukemia


Myelodysplastic Syndrome


Myeloproliferative Neoplasm


Recurrent Chronic Myelomonocytic Leukemia


Recurrent Myelodysplastic Syndrome


Recurrent Myeloproliferative Neoplasm
RECRUITING
NCT07124000
DESTINY-PANTUMOUR04
100 Enrollment(s)
17 Study location(s)
OBSERVATIONAL (None)
Adenocarcinoma (NOS)


Anal Cancer


Bladder Cancer


Cervical Cancer


Endometrial Cancer


Esophageal Cancer


Gall Bladder Cancer


Gastrointestinal Stromal Tumour


Head and Neck Cancer


Liver Cancer


Melanoma


Mouth Cancer


Nasopharangeal Cancer


Neuroendocrine, Gastrointestinal Cancer


Ovarian Cancer


Pancreatic Cancer


Prostate Cancer


Renal Cell Carcinoma


Salivary Gland Cancer


Sarcoma


Small Cell Lung Cancer


Testicular Cancer


Throat Cancer


Thyroid Cancer


Urethral Cancer


Vaginal Cancer


Vulvar Cancer
RECRUITING
NCT07060807
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
1,000 Enrollment(s)
174 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Neoplasms
RECRUITING
NCT06578247
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
700 Enrollment(s)
288 Study location(s)
INTERVENTIONAL (PHASE3)
Leukemia
RECRUITING
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
768 Enrollment(s)
108 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


Metastatic Gastric Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma


Esophageal Adenocarcinoma


Colorectal Cancer
ACTIVE_NOT_RECRUITING
NCT06172127
PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer
165 Enrollment(s)
36 Study location(s)
INTERVENTIONAL (PHASE2)
HER2-positive Breast Cancer