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RECRUITING
NCT06364410
Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors
48 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Clinical Stage III Gastric Cancer AJCC v8


Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8


Clinical Stage IV Gastric Cancer AJCC v8


Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8


Locally Advanced Gastric Carcinoma


Locally Advanced Gastroesophageal Junction Adenocarcinoma


Locally Advanced Malignant Solid Neoplasm


Metastatic Gastric Carcinoma


Metastatic Gastroesophageal Junction Adenocarcinoma


Metastatic Malignant Solid Neoplasm


Unresectable Gastric Carcinoma


Unresectable Gastroesophageal Junction Adenocarcinoma


Unresectable Malignant Solid Neoplasm
NOT_YET_RECRUITING
NCT06311214
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
500 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Malignant Solid Neoplasm


Metastatic Malignant Solid Neoplasm
ACTIVE_NOT_RECRUITING
NCT04739761
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
506 Enrollment(s)
81 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
ACTIVE_NOT_RECRUITING
NCT04618913
Anticoagulation in Patients With Venous Thromboembolism and Cancer
1 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Neoplasms


Embolism
ACTIVE_NOT_RECRUITING
NCT04494425
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
866 Enrollment(s)
294 Study location(s)
INTERVENTIONAL (PHASE3)
Advanced or Metastatic Breast Cancer
ACTIVE_NOT_RECRUITING
NCT04294628
Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer
63 Enrollment(s)
6 Study location(s)
INTERVENTIONAL (PHASE1)
Advanced Malignant Solid Neoplasm


HER2-Positive Breast Carcinoma


Metastatic Malignant Solid Neoplasm


Refractory Malignant Solid Neoplasm


Unresectable Malignant Solid Neoplasm
RECRUITING
NCT06435429
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
550 Enrollment(s)
63 Study location(s)
INTERVENTIONAL (PHASE3)
Metastatic HER2-positive Breast Cancer
RECRUITING
NCT06772246
A Study to Evaluate QTc Prolongation With Quizartinib in Healthy Subjects Under Rapid Acceleration of Heart Rate
70 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Healthy Subjects