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ACTIVE_NOT_RECRUITING
NCT04639219
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
102 Enrollment(s)
30 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
NOT_YET_RECRUITING
NCT06824168
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
130 Enrollment(s)
4 Study location(s)
INTERVENTIONAL (PHASE2)
Acute Myeloid Leukemia


Leukemia
RECRUITING
NCT06439693
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
72 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer Female


Breast Cancer


Breast Cancer Metastatic


Estrogen Receptor-positive Breast Cancer


HER2-positive Breast Cancer


Stage IV Breast Cancer
TERMINATED
NCT03248492
A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1)
253 Enrollment(s)
99 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer
RECRUITING
NCT06665178
Genomic and Transcriptomic Predictors of Sequential SG Sensitivity After T-DXd in ER+/HER2-Low Metastatic Breast Cancer
20 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer
ACTIVE_NOT_RECRUITING
NCT03742102
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
242 Enrollment(s)
32 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Triple Negative Breast Neoplasms
RECRUITING
NCT05945732
DESTINY Breast Respond HER2-low Europe
1,350 Enrollment(s)
198 Study location(s)
OBSERVATIONAL (None)
Unresectable Breast Cancer


Metastatic Breast Cancer


HER2-low Expressing Breast Cancer
COMPLETED
NCT04420598
DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease
41 Enrollment(s)
16 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Breast Cancer


HER2-positive Breast Cancer


Brain Metastases


Leptomeningeal Metastasis