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ACTIVE_NOT_RECRUITING
NCT05113251
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
927 Enrollment(s)
145 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Neoplasms
Breast Cancer
HER2-positive Early Breast Cancer
ACTIVE_NOT_RECRUITING
NCT04739761
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
506 Enrollment(s)
81 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
RECRUITING
NCT07753200
Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and Coronary Artery Disease
3,000 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE4)
Atrial Fibrillation (AF)
Coronary Arterial Disease (CAD)
RECRUITING
NCT07597993
BEYOND Study: A Multicentre, Prospective, Observational Study of Real-world Treatment Patterns and Outcomes of Trastuzumab Deruxtecan in Patients With HR Positive, HER2-low or Ultra-low Metastatic Breast Cancer Previously Treated With Endocrine Therapy
109 Enrollment(s)
9 Study location(s)
OBSERVATIONAL (None)
Breast Cancer
RECRUITING
NCT06731478
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
726 Enrollment(s)
250 Study location(s)
INTERVENTIONAL (PHASE3)
Gastric Cancer


Gastroesophageal Junction Cancer
RECRUITING
NCT07704918
Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
40 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
Melanoma
RECRUITING
NCT06328062
Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
80 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
Pain Postoperative


Osteoarthritis


Total Knee Arthroplasty
RECRUITING
NCT06439693
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
72 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer Female


Breast Cancer


Breast Cancer Metastatic


Estrogen Receptor-positive Breast Cancer


HER2-positive Breast Cancer


Stage IV Breast Cancer