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RECRUITING
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
768 Enrollment(s)
101 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


Metastatic Gastric Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma


Esophageal Adenocarcinoma


Colorectal Cancer
RECRUITING
NCT05417594
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
695 Enrollment(s)
33 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Advanced Solid Malignancies
RECRUITING
NCT07022483
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
710 Enrollment(s)
17 Study location(s)
INTERVENTIONAL (PHASE3)
Endometrial Cancer
ACTIVE_NOT_RECRUITING
NCT04556773
A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer
138 Enrollment(s)
37 Study location(s)
INTERVENTIONAL (PHASE1)
Metastatic Breast Cancer
RECRUITING
NCT04128748
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
52 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts More Than 10 Percent of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory Myelodysplastic Syndrome
RECRUITING
NCT04047641
Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
80 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts 20 Percent or More of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Biphenotypic Leukemia


Recurrent Acute Myeloid Leukemia


Recurrent High Risk Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory High Risk Myelodysplastic Syndrome
RECRUITING
NCT07281001
A Study to Assess the Efficiency of Trastuzumab Deruxtecan in Russian Breast Cancer Patients
60 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
HER2-positive Breast Cancer


Trastuzumab Deruxtecan
RECRUITING
NCT06630130
Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer
50 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Stomach Neoplasms