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RECRUITING
NCT06846996
Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China
260 Enrollment(s)
36 Study location(s)
OBSERVATIONAL (None)
HER2-positive Gastric Cancer


HER2-positive Gastroesophageal Junction
COMPLETED
NCT06833268
Real-world Outcomes of Patients With HER2+ Metastatic Breast Cancer After Treatment With Trastuzumab Deruxtecan
228 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
HER2-positive Breast Cancer
RECRUITING
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
582 Enrollment(s)
53 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


Metastatic Gastric Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma


Esophageal Adenocarcinoma
RECRUITING
NCT05048797
A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
450 Enrollment(s)
163 Study location(s)
INTERVENTIONAL (PHASE3)
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
COMPLETED
NCT03430661
A Study to Investigate the Interaction Between ACT-246475 and Clopidogrel, Prasugrel, and Ticagrelor in Healthy Subjects
77 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Healthy
NOT_YET_RECRUITING
NCT06494111
Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)
295 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Lymphedema


Fibrosis
RECRUITING
NCT06058988
Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer
30 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Brain Cancer


Glioblastoma


Metastatic Cancer


Leptomeningeal Metastasis


Recurrent Glioblastoma
RECRUITING
NCT06727227
Real-world Study of Trastuzumab Deruxtecan in Patients With Unresectable or Metastatic HER2-low Breast Cancer
135 Enrollment(s)
14 Study location(s)
OBSERVATIONAL (None)
Breast Cancer