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ACTIVE_NOT_RECRUITING
NCT06100874
A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN)
28 Enrollment(s)
4 Study location(s)
INTERVENTIONAL (PHASE2)
Her 2 Positive Breast Cancer


Breast Cancer Female


Breast Cancer Metastatic
RECRUITING
NCT07428044
A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer
14 Enrollment(s)
10 Study location(s)
INTERVENTIONAL (PHASE2)
Non-Small Cell Lung Cancer


Non-small Cell Lung Cancer Stage II


Non-Small Cell Lung Cancer Stage IIIA


Non-Small Cell Lung Cancer Stage IIIB
RECRUITING
NCT07098975
Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)
154 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE2)
Preeclampsia (PE)


Intrauterine Growth Restriction (IUGR)


Placental Insufficiency
RECRUITING
NCT06058988
Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer
30 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Brain Cancer


Glioblastoma


Metastatic Cancer


Leptomeningeal Metastasis


Recurrent Glioblastoma
RECRUITING
NCT05376878
An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis
10 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE4)
Anatomic Stage IV Breast Cancer AJCC v8


Metastatic Breast Carcinoma


Metastatic Malignant Neoplasm in the Brain
ACTIVE_NOT_RECRUITING
NCT05113251
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
927 Enrollment(s)
146 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Neoplasms


Breast Cancer


HER2-positive Early Breast Cancer
RECRUITING
NCT04379596
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
450 Enrollment(s)
100 Study location(s)
INTERVENTIONAL (PHASE2)
Gastric Cancer
ACTIVE_NOT_RECRUITING
NCT04784715
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)
1,157 Enrollment(s)
283 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer; HER2-positive; Metastatic