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COMPLETED
NCT01892371
Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
73 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
FLT3 Gene Mutation Negative


FLT3 Internal Tandem Duplication Positive


Recurrent Acute Myeloid Leukemia


Recurrent Chronic Myelomonocytic Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory Chronic Myelomonocytic Leukemia


Refractory Myelodysplastic Syndrome
RECRUITING
NCT05868226
PRE-I-SPY Phase I/Ib Oncology Platform Program
124 Enrollment(s)
7 Study location(s)
INTERVENTIONAL (PHASE1)
HER2-positive Breast Cancer


Metastatic Cancer


Metastatic Breast Cancer


Metastatic


HER2-positive Metastatic Breast Cancer


HER2 Mutation-Related Tumors


HER-2 Protein Overexpression


HER2-negative Breast Cancer


Triple Negative Breast Cancer


HR Positive


Hormone Receptor-positive Breast Cancer


Estrogen Receptor Positive Tumor


Progesterone Receptor-positive Breast Cancer


Hormone Receptor Negative Breast Carcinoma


Solid Tumor


Solid Tumor, Adult


Solid Carcinoma


HER2 Low Breast Cancer


HER2 Low Breast Carcinoma


ER Positive Breast Cancer


PR-positive Breast Cancer
RECRUITING
NCT06439693
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
72 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer Female


Breast Cancer


Breast Cancer Metastatic


Estrogen Receptor-positive Breast Cancer


HER2-positive Breast Cancer


Stage IV Breast Cancer
COMPLETED
NCT04014075
DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)
79 Enrollment(s)
37 Study location(s)
INTERVENTIONAL (PHASE2)
Adenocarcinoma Gastric Stage IV With Metastases


Adenocarcinoma - GEJ
NOT_YET_RECRUITING
NCT06900725
Low Dose Edoxaban in Elderly Patients With AF and a History of Stroke
300 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2|||PHASE3)
Elderly


Atrial Fibrillation (AF)


Ischemic Stroke
RECRUITING
NCT06731803
Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma
36 Enrollment(s)
11 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Esophagogastric Adenocarcinoma
RECRUITING
NCT06578247
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
700 Enrollment(s)
256 Study location(s)
INTERVENTIONAL (PHASE3)
Leukemia
ACTIVE_NOT_RECRUITING
NCT04494425
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
866 Enrollment(s)
294 Study location(s)
INTERVENTIONAL (PHASE3)
Advanced or Metastatic Breast Cancer