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SUSPENDED
NCT04616560
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma
77 Enrollment(s)
28 Study location(s)
INTERVENTIONAL (PHASE2)
Osteosarcoma


Recurrent Osteosarcoma
RECRUITING
NCT04553770
Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
88 Enrollment(s)
9 Study location(s)
INTERVENTIONAL (PHASE2)
Early-stage Breast Cancer


Hormone Receptor Positive Breast Carcinoma


Invasive Breast Cancer


Stage II Breast Cancer


Stage IIA Breast Cancer


Stage IIB Breast Cancer


Stage III Breast Cancer
SUSPENDED
NCT04585958
Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
55 Enrollment(s)
4 Study location(s)
INTERVENTIONAL (PHASE1)
Metastatic Malignant Solid Neoplasm


Platinum-Resistant Ovarian High Grade Serous Adenocarcinoma


Unresectable Malignant Solid Neoplasm
RECRUITING
NCT07065435
RC48 Plus Bevacizumab or Pyrotinib in HER2-Positive Metastatic Breast Cancer After T-DXd Failure: A Phase II Study
74 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
HER2 + Breast Cancer
ACTIVE_NOT_RECRUITING
NCT05650879
ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer
198 Enrollment(s)
39 Study location(s)
INTERVENTIONAL (PHASE1)
HER2 Mutant Non-small Cell Lung Cancer


HER2-positive Metastatic Breast Cancer


HER2 Gene Mutation


HER2 Amplification
RECRUITING
NCT05408845
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
146 Enrollment(s)
120 Study location(s)
INTERVENTIONAL (PHASE2)
Metastatic Salivary Gland Carcinoma


Recurrent Salivary Gland Carcinoma


Stage III Major Salivary Gland Cancer AJCC v8


Stage IV Major Salivary Gland Cancer AJCC v8


Unresectable Salivary Gland Carcinoma
ACTIVE_NOT_RECRUITING
NCT04294628
Testing the Biological Effects of DS-8201a on Patients With Advanced Cancer
63 Enrollment(s)
6 Study location(s)
INTERVENTIONAL (PHASE1)
Advanced Malignant Solid Neoplasm


HER2-Positive Breast Carcinoma


Metastatic Malignant Solid Neoplasm


Refractory Malignant Solid Neoplasm


Unresectable Malignant Solid Neoplasm
RECRUITING
NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
580 Enrollment(s)
41 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer