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RECRUITING
NCT06311214
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
500 Enrollment(s)
29 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Malignant Solid Neoplasm


Metastatic Malignant Solid Neoplasm
NOT_YET_RECRUITING
NCT07880821
Perioperative Mirogabalin for Pain Relief After Modified Radical Mastectomy
50 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
Breast Cancer


Post Operative Pain
NOT_YET_RECRUITING
NCT07828054
Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab Deruxtecan
244 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer


Interstitial Lung Disease (ILD)
RECRUITING
NCT07683754
T-DXd Based Therapy Followed by Endocrine Therapy Plus Dual HER2 Blockade in First-line HER2+/ HR+ Metastatic Breast Cancer and Retreatment With T-DXd
200 Enrollment(s)
5 Study location(s)
INTERVENTIONAL (PHASE3)
Advanced Breast Cancer


Metastatic Breast Cancer


HER2 Positive


HR Positive
RECRUITING
NCT07137416
Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer
36 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE1)
Anatomic Stage III Breast Cancer AJCC v8


Anatomic Stage IV Breast Cancer AJCC v8


Invasive Breast Carcinoma


Locally Advanced Breast Carcinoma


Metastatic Breast Carcinoma


Metastatic HER2-Low Breast Carcinoma


Metastatic HER2-Positive Breast Carcinoma


Metastatic Hormone Receptor-Positive Breast Carcinoma


Metastatic Malignant Solid Neoplasm


Metastatic Triple-Negative Breast Carcinoma


Unresectable Breast Carcinoma


Unresectable HER2-Low Breast Carcinoma


Unresectable HER2-Positive Breast Carcinoma


Unresectable Hormone Receptor-Positive Breast Carcinoma


Unresectable Malignant Solid Neoplasm


Unresectable Triple-Negative Breast Carcinoma
RECRUITING
NCT07098975
Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)
154 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE2)
Preeclampsia (PE)


Intrauterine Growth Restriction (IUGR)


Placental Insufficiency
RECRUITING
NCT07069712
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
100 Enrollment(s)
70 Study location(s)
INTERVENTIONAL (PHASE2)
Gastroesophageal Adenocarcinoma
RECRUITING
NCT06764875
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
840 Enrollment(s)
304 Study location(s)
INTERVENTIONAL (PHASE3)
HER2-positive Gastric Cancer


Gastroesophageal Junction Adenocarcinoma