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RECRUITING
NCT06435429
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
550 Enrollment(s)
166 Study location(s)
INTERVENTIONAL (PHASE3)
Metastatic HER2-positive Breast Cancer
RECRUITING
NCT04379596
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
413 Enrollment(s)
100 Study location(s)
INTERVENTIONAL (PHASE2)
Gastric Cancer
RECRUITING
NCT02390752
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
54 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Neurofibroma, Plexiform


Precursor Cell Lymphoblastic Leukemia-Lymphoma


Leukemia, Promyelocytic, Acute


Sarcoma
RECRUITING
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
582 Enrollment(s)
101 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


Metastatic Gastric Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma


Esophageal Adenocarcinoma
RECRUITING
NCT06486883
Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
200 Enrollment(s)
29 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Breast Cancer


Advanced Breast Carcinoma


Hormone Receptor Positive Breast Carcinoma
RECRUITING
NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
792 Enrollment(s)
42 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer
RECRUITING
NCT06210776
A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH)
800 Enrollment(s)
54 Study location(s)
OBSERVATIONAL (None)
HER2-positive Breast Cancer


HER2-low Breast Cancer


Breast Cancer


Advanced Cancer
RECRUITING
NCT05982678
Basket Study for Oligo-metastatic Breast Cancer
72 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
HER2-positive Breast Cancer