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RECRUITING
NCT06731478
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
726 Enrollment(s)
248 Study location(s)
INTERVENTIONAL (PHASE3)
Gastric Cancer


Gastroesophageal Junction Cancer
RECRUITING
NCT06578247
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
700 Enrollment(s)
283 Study location(s)
INTERVENTIONAL (PHASE3)
Leukemia
RECRUITING
NCT07069712
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
100 Enrollment(s)
68 Study location(s)
INTERVENTIONAL (PHASE2)
Gastroesophageal Adenocarcinoma
RECRUITING
NCT06899126
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
686 Enrollment(s)
74 Study location(s)
INTERVENTIONAL (PHASE3)
Non-small Cell Lung Cancer
RECRUITING
NCT06824168
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
130 Enrollment(s)
58 Study location(s)
INTERVENTIONAL (PHASE2)
Acute Myeloid Leukemia


Leukemia
RECRUITING
NCT06409390
Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
15 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Metastatic Breast Cancer
RECRUITING
NCT06311214
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
500 Enrollment(s)
23 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Malignant Solid Neoplasm


Metastatic Malignant Solid Neoplasm
RECRUITING
NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
600 Enrollment(s)
245 Study location(s)
INTERVENTIONAL (PHASE3)
Endometrial Cancer