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RECRUITING
NCT07069712
A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma
100 Enrollment(s)
68 Study location(s)
INTERVENTIONAL (PHASE2)
Gastroesophageal Adenocarcinoma
RECRUITING
NCT07124000
DESTINY-PANTUMOUR04
100 Enrollment(s)
8 Study location(s)
OBSERVATIONAL (None)
Adenocarcinoma (NOS)


Anal Cancer


Bladder Cancer


Cervical Cancer


Endometrial Cancer


Esophageal Cancer


Gall Bladder Cancer


Gastrointestinal Stromal Tumour


Head and Neck Cancer


Liver Cancer


Melanoma


Mouth Cancer


Nasopharangeal Cancer


Neuroendocrine, Gastrointestinal Cancer


Ovarian Cancer


Pancreatic Cancer


Prostate Cancer


Renal Cell Carcinoma


Salivary Gland Cancer


Sarcoma


Small Cell Lung Cancer


Testicular Cancer


Throat Cancer


Thyroid Cancer


Urethral Cancer


Vaginal Cancer


Vulvar Cancer
RECRUITING
NCT06467357
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer
620 Enrollment(s)
262 Study location(s)
INTERVENTIONAL (PHASE3)
Biliary Tract Cancer
RECRUITING
NCT04482309
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
468 Enrollment(s)
123 Study location(s)
INTERVENTIONAL (PHASE2)
Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer


Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
ACTIVE_NOT_RECRUITING
NCT05633979
Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
17 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Breast Cancer
ACTIVE_NOT_RECRUITING
NCT04618913
Anticoagulation in Patients With Venous Thromboembolism and Cancer
1 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Neoplasms


Embolism
NOT_YET_RECRUITING
NCT07318389
ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer
100 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (EARLY_PHASE1)
Dynamic Tumor Resistance


Metastatic Colorectal Cancer
RECRUITING
NCT06989112
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
600 Enrollment(s)
247 Study location(s)
INTERVENTIONAL (PHASE3)
Endometrial Cancer