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COMPLETED
NCT06504719
Safety and Efficacy Real-world Data of Trastuzumab Deruxtecan and Sacituzumab Govitecan
312 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Breast Cancer


Metastatic Cancer
NOT_YET_RECRUITING
NCT07130344
PERCIST Evaluation of Trastuzumab Deruxtecan in the Treatment of HER2 Low Breast Cancer
262 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
Metastatic Breast Cancer


HER 2 Low-expressing Breast Cancer
ACTIVE_NOT_RECRUITING
NCT04257162
HER2-PREDICT: Translational Study of Tumor Samples From Patients Treated With Trastuzumab Deruxtecan (T-DXd; DS-8201a)
180 Enrollment(s)
15 Study location(s)
INTERVENTIONAL (NA)
Metastatic Cancer
NOT_YET_RECRUITING
NCT07157956
CVL006 Combination Therapy in Advanced Solid Tumors
318 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Advanced Solid Tumor
NOT_YET_RECRUITING
NCT07152782
T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
202 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer With Brain Metastasis


HER2-positive Breast Cancer
NOT_YET_RECRUITING
NCT07151586
Testing Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an Alterning Pattern to Patients With Metastatic or Locally Advanced Triple-negative Breast Cancer
260 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE2)
Triple Negative Breast Neoplasms


Neoplasm Metastasis


HER 2 Low-expressing Breast Cancer
NOT_YET_RECRUITING
NCT07150208
T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis
140 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer With Brain Metastasis


HER2-low Expressing Breast Cancer
RECRUITING
NCT05900206
Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer
370 Enrollment(s)
7 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer