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ACTIVE_NOT_RECRUITING
NCT04257162
HER2-PREDICT: Translational Study of Tumor Samples From Patients Treated With Trastuzumab Deruxtecan (T-DXd; DS-8201a)
180 Enrollment(s)
15 Study location(s)
INTERVENTIONAL (NA)
Metastatic Cancer
NOT_YET_RECRUITING
NCT07157956
CVL006 Combination Therapy in Advanced Solid Tumors
318 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Advanced Solid Tumor
NOT_YET_RECRUITING
NCT07086768
Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors
57 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Solid Tumor


Advanced Solid Tumor


Metastatic Solid Tumor
NOT_YET_RECRUITING
NCT07152782
T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis
202 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer With Brain Metastasis


HER2-positive Breast Cancer
NOT_YET_RECRUITING
NCT07151586
Testing Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an Alterning Pattern to Patients With Metastatic or Locally Advanced Triple-negative Breast Cancer
260 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE2)
Triple Negative Breast Neoplasms


Neoplasm Metastasis


HER 2 Low-expressing Breast Cancer
NOT_YET_RECRUITING
NCT07150208
T-DXd With or Without Bevacizumab for HER2-low Breast Cancer With Brain Metastasis
140 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer With Brain Metastasis


HER2-low Expressing Breast Cancer
RECRUITING
NCT05900206
Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer
370 Enrollment(s)
7 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer
ACTIVE_NOT_RECRUITING
NCT05246514
A Single Arm Phase 2 Study to Evaluate Efficacy and Safety of Trastuzumab Deruxtecan for Patients With HER2 Mutant NSCLC
72 Enrollment(s)
28 Study location(s)
INTERVENTIONAL (PHASE2)
HER2-mutant Non-Small Cell Lung Cancer