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NOT_YET_RECRUITING
NCT07478991
Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)
376 Enrollment(s)
51 Study location(s)
INTERVENTIONAL (PHASE3)
Acute Myeloid Leukemia, Adult
RECRUITING
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
768 Enrollment(s)
103 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


Metastatic Gastric Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma


Esophageal Adenocarcinoma


Colorectal Cancer
RECRUITING
NCT07060807
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
1,000 Enrollment(s)
149 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Neoplasms
RECRUITING
NCT06731478
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
726 Enrollment(s)
250 Study location(s)
INTERVENTIONAL (PHASE3)
Gastric Cancer


Gastroesophageal Junction Cancer
RECRUITING
NCT06364410
Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors
48 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Clinical Stage III Gastric Cancer AJCC v8


Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8


Clinical Stage IV Gastric Cancer AJCC v8


Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8


Locally Advanced Gastric Carcinoma


Locally Advanced Gastroesophageal Junction Adenocarcinoma


Locally Advanced Malignant Solid Neoplasm


Metastatic Gastric Carcinoma


Metastatic Gastroesophageal Junction Adenocarcinoma


Metastatic Malignant Solid Neoplasm


Unresectable Gastric Carcinoma


Unresectable Gastroesophageal Junction Adenocarcinoma


Unresectable Malignant Solid Neoplasm
RECRUITING
NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
792 Enrollment(s)
45 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer
RECRUITING
NCT06731803
Platform Trial Evaluating Treatment of Neoadjuvant Trastuzumab-deruxtecan Containing Combination Therapies for HER2+, Resectable Esophagogastric Adenocarcinoma
36 Enrollment(s)
11 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Esophagogastric Adenocarcinoma
RECRUITING
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
420 Enrollment(s)
44 Study location(s)
INTERVENTIONAL (PHASE1)
Acute Myeloid Leukemia


Mixed Lineage Leukemia Gene Mutation


Refractory AML


AML With Mutated NPM1


Acute Myeloid Leukemia Recurrent


Acute Myeloid Leukemia, in Relapse


NPM1 Mutation


KMT2Ar


Myeloid Sarcoma


Nucleophosmin 1-mutated Acute Myeloid Leukemia