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RECRUITING
NCT07198724
ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer
65 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer


HER2 Low Breast Carcinoma


HER2-negative Breast Cancer


Breast Cancer


Breast Cancer Female
RECRUITING
NCT05704829
NeoAdjuvant Therapy With Trastuzumab-deruxtecan Versus Chemotherapy+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer
702 Enrollment(s)
44 Study location(s)
INTERVENTIONAL (PHASE2)
HER2-positive Early Breast Cancer
COMPLETED
NCT05035277
AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation
360 Enrollment(s)
3 Study location(s)
INTERVENTIONAL (PHASE3)
Aortic Stenosis
TERMINATED
NCT04100135
GORE® CARDIOFORM Septal Occluder Migraine Clinical Study
7 Enrollment(s)
15 Study location(s)
INTERVENTIONAL (NA)
Migraine


Patent Foramen Ovale


PFO - Patent Foramen Ovale
NOT_YET_RECRUITING
NCT07630103
Efficacy and Safety of Trastuzumab Rezetecan or Trastuzumab Deruxtecan in Advanced Breast Cancer
100 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Breast Cancer
RECRUITING
NCT07086768
Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors
57 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Solid Tumor


Advanced Solid Tumor


Metastatic Solid Tumor
COMPLETED
NCT04981041
Escalated Single Platelet Inhibition for One Month Plus NOAC in Patients With Atrial Fibrillation and ACS Undergoing PCI
602 Enrollment(s)
37 Study location(s)
INTERVENTIONAL (PHASE4)
Acute Coronary Syndrome


Atrial Fibrillation
ACTIVE_NOT_RECRUITING
NCT04128748
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
52 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts More Than 10 Percent of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory Myelodysplastic Syndrome