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ACTIVE_NOT_RECRUITING
NCT04556773
A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer
138 Enrollment(s)
37 Study location(s)
INTERVENTIONAL (PHASE1)
Metastatic Breast Cancer
RECRUITING
NCT04128748
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
52 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts More Than 10 Percent of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory Myelodysplastic Syndrome
RECRUITING
NCT04047641
Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
80 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts 20 Percent or More of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Biphenotypic Leukemia


Recurrent Acute Myeloid Leukemia


Recurrent High Risk Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory High Risk Myelodysplastic Syndrome
RECRUITING
NCT07281001
A Study to Assess the Efficiency of Trastuzumab Deruxtecan in Russian Breast Cancer Patients
60 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
HER2-positive Breast Cancer


Trastuzumab Deruxtecan
RECRUITING
NCT06630130
Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer
50 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Stomach Neoplasms
RECRUITING
NCT06085755
Trastuzumab Deruxtecan(T-DXd) and Afatinib Combination in HER2-low Advanced Gastric Cancer
61 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Stomach Neoplasm
COMPLETED
NCT03463317
Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy
912 Enrollment(s)
42 Study location(s)
INTERVENTIONAL (PHASE4)
Atrial Fibrillation
ACTIVE_NOT_RECRUITING
NCT04538742
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
245 Enrollment(s)
72 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Metastatic Breast Cancer