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WITHDRAWN
NCT06585969
A Randomised Trial Comparing Trastuzumab Deruxtecan to CDK4/6 Inhibitors in Non-luminal A, ER-positive/HER2-low Metastatic Breast Cancer
0 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE3)
Metastatic Breast Cancer


ER-positive Breast Cancer


Luminal B


Her2 Enriched


Basal Like
RECRUITING
NCT05993234
A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)
257 Enrollment(s)
76 Study location(s)
OBSERVATIONAL (None)
HER2-positive Advanced Gastric Cancer


HER2-positive Gastroesophageal Junction Adenocarcinoma
RECRUITING
NCT05945732
DESTINY Breast Respond HER2-low Europe
1,155 Enrollment(s)
211 Study location(s)
OBSERVATIONAL (None)
Unresectable Breast Cancer


Metastatic Breast Cancer


HER2-low Expressing Breast Cancer
RECRUITING
NCT06769490
Dose Escalation and Expansion of Ziftomenib in Combination With Quizartinib in Acute Myeloid Leukemia
44 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Acute Myeloid Leukemia
ACTIVE_NOT_RECRUITING
NCT04739761
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
506 Enrollment(s)
81 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
RECRUITING
NCT06435429
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
550 Enrollment(s)
166 Study location(s)
INTERVENTIONAL (PHASE3)
Metastatic HER2-positive Breast Cancer
ENROLLING_BY_INVITATION
NCT06250777
Efficacy and Safety of T-DXd in HER2-mutant Advanced Lung Cancer Patients With Asymptomatic Brain Metastases
27 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Non Small Cell Lung Cancer
COMPLETED
NCT01903694
Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma
474 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE3)
Child-Pugh A Hepatocellular Carcinoma