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RECRUITING
NCT06819007
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
582 Enrollment(s)
205 Study location(s)
INTERVENTIONAL (PHASE3)
Ovarian Cancer
RECRUITING
NCT04986579
Scalp Cooling in MBC
120 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE2)
Metastatic Breast Cancer


Chemotherapy-induced Alopecia
RECRUITING
NCT07653893
A Phase II Observational Clinical Study on the Relationship Between Cerebrospinal Fluid Drug Concentration and Efficacy of Trastuzumab Deruxtecan in Central Nervous System Metastatic Breast Cancer
60 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Central Nervous System (CNS) Metastases


Breast Cancer
RECRUITING
NCT07647016
Trastuzumab Deruxtecan Plus ivonescImab for Hormone Receptor-positive HER2 Negative Advanced Breast Cancer Study
53 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer
RECRUITING
NCT05950945
Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer
250 Enrollment(s)
88 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
RECRUITING
NCT04047641
Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
80 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts 20 Percent or More of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Biphenotypic Leukemia


Recurrent Acute Myeloid Leukemia


Recurrent High Risk Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory High Risk Myelodysplastic Syndrome
NOT_YET_RECRUITING
NCT07619521
Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a, for Advanced Pancreatic Ductal Adenocarcinoma
31 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Advanced Pancreatic Ductal Adenocarcinoma


Metastatic Pancreatic Ductal Adenocarcinoma


Stage III Pancreatic Cancer AJCC v8


Stage IV Pancreatic Cancer AJCC v8


Unresectable Pancreatic Ductal Adenocarcinoma
NOT_YET_RECRUITING
NCT07318389
ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer
100 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (EARLY_PHASE1)
Dynamic Tumor Resistance


Metastatic Colorectal Cancer