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COMPLETED
NCT06386263
HER-TEMPO - Real World Treatment-related Outcomes on T-DXd in Canada
22 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Unresectable Breast Cancer


Metastatic Breast Cancer


HER2-low Expressing Breast Cancer


HER2-positive Breast Cancer
RECRUITING
NCT06740799
Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment
12 Enrollment(s)
3 Study location(s)
INTERVENTIONAL (PHASE1)
Hepatic Impairment
RECRUITING
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
420 Enrollment(s)
44 Study location(s)
INTERVENTIONAL (PHASE1)
Acute Myeloid Leukemia


Mixed Lineage Leukemia Gene Mutation


Refractory AML


AML With Mutated NPM1


Acute Myeloid Leukemia Recurrent


Acute Myeloid Leukemia, in Relapse


NPM1 Mutation


KMT2Ar


Myeloid Sarcoma


Nucleophosmin 1-mutated Acute Myeloid Leukemia
RECRUITING
NCT04493138
Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations
58 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Chronic Myelomonocytic Leukemia


Myelodysplastic Syndrome


Myeloproliferative Neoplasm


Recurrent Chronic Myelomonocytic Leukemia


Recurrent Myelodysplastic Syndrome


Recurrent Myeloproliferative Neoplasm
RECRUITING
NCT04635111
A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment
30 Enrollment(s)
8 Study location(s)
OBSERVATIONAL (None)
Hepatotoxicity


Tenosynovial Giant Cell Tumor
ACTIVE_NOT_RECRUITING
NCT03734029
Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]
557 Enrollment(s)
208 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
COMPLETED
NCT04539938
A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer
70 Enrollment(s)
140 Study location(s)
INTERVENTIONAL (PHASE2)
HER2 Positive Breast Cancer
COMPLETED
NCT05804747
A Study to Evaluate Effectiveness and Safety of Edoxaban in Patients 80 Years of Age or Older With Nonvalvular Atrial Fibrillation
1,204 Enrollment(s)
33 Study location(s)
OBSERVATIONAL (None)
Atrial Fibrillation