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RECRUITING
NCT05274048
Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients
18 Enrollment(s)
3 Study location(s)
INTERVENTIONAL (PHASE1)
Gastric Cancer


Gastrointestinal Cancer


HER2 Gene Mutation
ACTIVE_NOT_RECRUITING
NCT03334617
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
528 Enrollment(s)
45 Study location(s)
INTERVENTIONAL (PHASE2)
Non-Small Cell Lung Cancer
RECRUITING
NCT06533826
TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
357 Enrollment(s)
11 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer


HER2-low Breast Cancer


Metastatic Breast Cancer


HER2-negative Breast Cancer
RECRUITING
NCT06271837
A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors
175 Enrollment(s)
31 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Solid Tumors (Excluding Gastric Cancer and Breast Cancer)
RECRUITING
NCT06750484
Trial of Trastuzumab Deruxtecan in Previously Treated HER2
40 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer Metastatic
ACTIVE_NOT_RECRUITING
NCT03529110
DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]
524 Enrollment(s)
164 Study location(s)
INTERVENTIONAL (PHASE3)
Breast Cancer
NOT_YET_RECRUITING
NCT07217938
Novel Treatment of Radiation Associated Dysphagia With Statins
48 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Radiation-associated Dysphagia


Head &Amp; Neck Cancer
ACTIVE_NOT_RECRUITING
NCT04639219
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
102 Enrollment(s)
30 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast