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RECRUITING
NCT05633979
Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer
37 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Breast Cancer
RECRUITING
NCT04379596
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
413 Enrollment(s)
100 Study location(s)
INTERVENTIONAL (PHASE2)
Gastric Cancer
RECRUITING
NCT03661307
Quizartinib, Decitabine, and Venetoclax in Treating Participants with Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome
73 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia
ACTIVE_NOT_RECRUITING
NCT04704934
Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)
490 Enrollment(s)
156 Study location(s)
INTERVENTIONAL (PHASE3)
Gastric Cancer, Adenocarcinoma


Gastroesophageal Junction Adenocarcinoma
COMPLETED
NCT04644237
Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)
152 Enrollment(s)
50 Study location(s)
INTERVENTIONAL (PHASE2)
Non-Small Cell Lung Cancer
ACTIVE_NOT_RECRUITING
NCT04488822
A Study of the Efficacy and Safety of Pexidartinib in Adult Subjects With TGCT
40 Enrollment(s)
9 Study location(s)
INTERVENTIONAL (PHASE3)
Tenosynovial Giant Cell Tumor
NOT_YET_RECRUITING
NCT06650501
Dabigatran for the Adjunctive Treatment of Staphylococcus Aureus Bacteremia
300 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE4)
Staphylococcus Aureus Endocarditis


Staphylococcus Aureus Septicemia


Staphylococcus Aureus Bacteremia


Staphylococcus Aureus Bloodstream Infection


S. Aureus Bacteremia


S. Aureus Bloodstream Infection
COMPLETED
NCT03901352
Study of Mirogabalin for Central Neuropathic Pain
300 Enrollment(s)
118 Study location(s)
INTERVENTIONAL (PHASE3)
Central Neuropathic Pain