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NOT_YET_RECRUITING
NCT07217938
Novel Treatment of Radiation Associated Dysphagia With Statins
48 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Radiation-associated Dysphagia


Head &Amp; Neck Cancer
ACTIVE_NOT_RECRUITING
NCT04639219
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
102 Enrollment(s)
30 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
COMPLETED
NCT06386263
HER-TEMPO - Real World Treatment-related Outcomes on T-DXd in Canada
22 Enrollment(s)
1 Study location(s)
OBSERVATIONAL (None)
Unresectable Breast Cancer


Metastatic Breast Cancer


HER2-low Expressing Breast Cancer


HER2-positive Breast Cancer
RECRUITING
NCT06740799
Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment
12 Enrollment(s)
3 Study location(s)
INTERVENTIONAL (PHASE1)
Hepatic Impairment
ACTIVE_NOT_RECRUITING
NCT03742102
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
243 Enrollment(s)
32 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Triple Negative Breast Neoplasms
RECRUITING
NCT06912763
Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)
250 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Fibrosis Syndrome


Lymphedema


Head &Amp; Neck Cancer


Fibrosis
RECRUITING
NCT03661307
Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome
73 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia
RECRUITING
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
420 Enrollment(s)
44 Study location(s)
INTERVENTIONAL (PHASE1)
Acute Myeloid Leukemia


Mixed Lineage Leukemia Gene Mutation


Refractory AML


AML With Mutated NPM1


Acute Myeloid Leukemia Recurrent


Acute Myeloid Leukemia, in Relapse


NPM1 Mutation


KMT2Ar


Myeloid Sarcoma


Nucleophosmin 1-mutated Acute Myeloid Leukemia