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RECRUITING
NCT06610825
Castrate Resistant Prostate Cancer Enhertu Therapy
60 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Prostate Cancer Metastatic


Prostate Cancer


CRPC
NOT_YET_RECRUITING
NCT06486883
Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype
200 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE2)
Advanced Breast Cancer


Advanced Breast Carcinoma


Hormone Receptor Positive Breast Carcinoma
RECRUITING
NCT04493138
Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations
58 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Chronic Myelomonocytic Leukemia


Myelodysplastic Syndrome


Myeloproliferative Neoplasm


Recurrent Chronic Myelomonocytic Leukemia


Recurrent Myelodysplastic Syndrome


Recurrent Myeloproliferative Neoplasm
COMPLETED
NCT06930937
To Compare and Evaluate the Oral Bioavailability of Edoxaban 60 mg Film Coated Tablet With That of Lixiana® 60 mg Filmtabletten (Film Coated Tablet) (Edoxaban) in Healthy, Adult, Human Subjects Under Fasting Conditions
42 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (NA)
Prevention of Stroke or Systemic Embolism


Deep Vein Thrombosis (DVT)


Pulmonary Embolism (PE)
RECRUITING
NCT04128748
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
52 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1|||PHASE2)
Acute Myeloid Leukemia


Blasts More Than 10 Percent of Bone Marrow Nucleated Cells


High Risk Myelodysplastic Syndrome


Recurrent Acute Myeloid Leukemia


Recurrent Myelodysplastic Syndrome


Refractory Acute Myeloid Leukemia


Refractory Myelodysplastic Syndrome
RECRUITING
NCT06819007
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer
582 Enrollment(s)
2 Study location(s)
INTERVENTIONAL (PHASE3)
Ovarian Cancer
RECRUITING
NCT06048718
T-DXd Therapy for HER2-low Breast Cancer Patients With Brain Metastases
27 Enrollment(s)
13 Study location(s)
INTERVENTIONAL (PHASE2)
Breast Cancer


Metastatic Breast Cancer
COMPLETED
NCT05524246
Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index
25 Enrollment(s)
1 Study location(s)
INTERVENTIONAL (PHASE1)
Hematopoietic Stem Cell Transplant (HSCT)


Endothelial Injury